As far as I can determine, only one camera has ever been designed ergonomically to fit the left hand, the Yashica Samurai half-frame series made in the late 1980s. I may be wrong, and if anyone out there knows of another lefty camera please let me know.
There were two versions of the Samurai, one for righties and one for lefties. Ironically the only product shots I can find show the right-handed version.
If you think the exterior is bizarre, check out the loading mechanism. It would definitely take a full frame brain to figure this thing out.
See what lefties have to deal with on a daily basis? Thank God I'm a righty with my trusty arsenal of righty cameras. Like this one:
Like most rangefinders, the Leica has controls on the right and viewfinder on the left. The idea is that you put your right eye to the viewfinder while your left eye can watch the scene unfold.
But I've never done it that way. I've always been a left-eyed photographer. I close my right eye, smush my nose against the back of the camera and squint with my left through the little window. My cameras tend to brass up on the back plate where my nose rubs. I'm not sure why I use my left eye, if it connects to the right brain or some other reason. It's just the way I do it. Even if I could use my right eye, I'd have to keep the left one closed. I can't concentrate on two things at once.
Now if only I could find my son a left-handed baseball bat...